Hypothyroidism-how important is this condition?

This is opposite of hyperthyroidism. Hypothyroidism in atrophy (wasting) thyroid and reduction in the secretion. The condition may be due to the pituitary gland, in this case it is referred to as secondary hypothyroidism, but if this is due to the inability of the hypothalamus is higher.

The condition may appear in childhood, in which case it's called cretinism; or in adulthood (Myxoedema).

Cretinism
Cretinism is a term used to describe hypothyroidism children or children who are usually caused by a deficiency of thyroid hormone.
Causes of cretinism
a. genetic defect: for unknown reasons, there is a genetic defect in the formation of the thyroid gland and its ability to secrete enough thyroid hormones that are required by its metabolic activity.
b. goitrous parents: mothers suffering from Zoba may not produce enough thyroid stimulating hormone (TSH) needed the fruit in its early stages. So when a child is born it can develop hypothyroidism later in life.
c. pituitary dysfunction: pituitary gland controls the activity of the thyroid gland. Pituitary gland dysfunction automatically affect the thyroid gland and reduces its development and its ability to secrete hormones, causing cretinism among children.
d. iodine: insufficient or total lack of iodine in soil and water special place leads to cretinism among children of the area. This is very common in the mountainous regions.

Signs and symptoms of cretinism
i. the extended language
II. dull facial expression
III. Preriorbital edema
IV. puffy limbs
v. thickened skin and lips
VI. problems feeding
VII. mental retardation
VIII. fetal growth
IX. accumulated temperature
x. coarse features
XI. zažmurit'sâ

Diagnostics
a. presentation of signs and symptoms may be key to diagnosis
b. radiograph of the epiphyses in children or ossification of the wrist or heel in infants will show the delay in bone age, compared to the true age of the child.
c. serum Tyroxine: there is usually a low concentration of serum thyroxine during the test.

Myxoedema
Myxoedema is the disorder that occurs in adults due to a lack of thyroid hormones. Myxoedema is more common, girls who are 45 years old and above.

Causes of myxoedema
i. exposure: exposure which may apply to treat goiter can lead to the complete destruction of thyroid and subsequently its inability to secrete hormones of the thyroid gland.
II. total thyroidectomy: surgical removal of a thyroid gland in the treatment of severe goiter or hyperthyroidism causes deficiency of thyroid hormone.
III. Goitrogens: consumption of foods high in goitrogen or ingestion of drugs, which contain goitrogen might lead to impairment in thyroid function.
IV. autoimmune chronic tireoidit: for unknown reasons, the body develops antibodies that attack the cells of the thyroid gland. It is a condition that is thyroiditis and Hashimoto's Thyroiditis is psychologically impossible it to produce thyroid hormones of the thyroid gland.
v. anti tyroid drugs: over dosage anti-thyroid drugs lead to hypothyroidism
VI. prolonged iodine
VII. disorder of the hypothalamic pituitary.

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